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OCR: uction of It is well established that ove y humoral o clinically calcitonin is not associated w syndrome, because calcitonir ver, detectable biological activity, rom overproduction of GRP or GI reported to neuroendocrine tumours ha omegaly, induce Cushing's syndrome e not observed in respectively. These syndrom rcinoma; the patients with small-cell 1 .te that the therefore it is reasonable to s e hormones are biological activities of these of peptide rather weak, and that the am h small-cell lung develop hormone that was produced neoplasm was not great enou nall-cell lung humoral syndromes, These features are not limite roduction, but carcinoma or to ectopic horm ma that produce are common to a variety of c bigacti ze su